2020年9月30日 星期三
諱疾忌醫
2020年8月13日 星期四
中西醫合作
作者: 蔡昇達
腦部核磁共振顯示右側丘腦梗塞(白色亮區),影響左腳的協調功能
三、
Acupuncture reduced the medical expenditure in migraine patients:
Real-world data of a 10-year national cohort study
在華人的文化中,中醫是很重要的一部份,相信中西醫互相合作可以給病人更好
的診斷及治療,讓個人、家庭、及社會更健康!
2020年6月27日 星期六
新冠肺炎神經學表現
作者: 蔡昇達
中國附醫神經部團隊做了系統性的回顧及統合分析
為第一線的臨床工作者總結了新冠肺炎的神經學表現
將最常見的神經學表現和比例總結成一張圖
還有其他較少見的神經相關症狀如腦炎、神經痛、小腦共濟失調、格林巴利症候群、米勒費雪症候群、顱內出血、多發性顱神經炎、肌張力不全等
可能的機轉為病毒感染造成的細胞激素(cytokines)、神經的侵犯(病毒從嗅神經進入)、病毒經由血流影響到神經系統等
收錄文獻的發表日期為 2019 年 12 月到 2020 年 04 月 30 日
從總數 2209 篇文章中做篩選
上圖是我們的文獻搜尋流程 (PRISMA)
也附上幾個重要症狀的 Forest Plot (森林圖)
先放上大家最好奇的嗅味覺異常之森林圖
再放上意識改變的森林圖
全文已於 2020.05.19 刋載於 Frontiers in Neurology (神經學前沿雜誌)
可至以下網址下載 PDF 全文
https://www.frontiersin.org/articles/10.3389/fneur.2020.00498/full
The Neurologic Manifestations of Coronavirus Disease 2019 Pandemic: A Systemic Review
謝謝蔡崇豪院長及呂明桂醫師的指導、謝謝楊家純醫師幫忙做出統計的森林圖
謝謝盧秀禎協助畫出精美的卡通圖
謝謝編輯(西班牙醫師)及三位審稿者(英國、法國、及巴西的研究者)給予的意見
大大提升我們文章的品質
希望透過這個簡要的整理,幫助前線的醫護人員們,節省閱讀文獻的時間、也更了解這個高傳染力的疾病!祈願世界的新冠疫情早日平息~~
2020年6月21日 星期日
2020年6月20日 星期六
Curriculum Vitae
Author: Sheng-Ta Tsai
Sheng-Ta Tsai, MD, PhD
Doctor Tsai has devoted his life to Parkinson’s disease, movement disorder, stroke care, and neurocritical disease. He is a member of the movement disorder group led by Professor Chon-Haw Tsai. He has joined the deep brain stimulation intra-operative multichannel microelectrode recording (MER) and has performed basic studies for Parkinson’s disease. He is also a stroke neurologist performing intra-arterial thrombectomy for hyperacute large artery occlusion patients. And in the intensive care unit, he takes care of patients with severe stroke, status epilepticus, or severe central nervous system infection. Doctor Tsai has won high reward in the improvement of patients, including the regaining consciousness. In the intensive care unit, he often says to patients, “Our goal is your being able to walk back home without others’ assistance.”
Employment:
Doctor in Taiwan, No. 049345, Taiwan Ministry of Health and Welfare
Neurologist in Taiwan, No. 1232, Taiwan Neurological Society
Acupuncture doctor, No. 2555, Chinese Medical Association of Acupuncture (CMAA)
SCI papers: (IF= Impact factor; R/C= Ranking/ Category, updated according to the 2025 JCR release; *corresponding author)
Systemic
review and meta-analysis: (3)
1. Chia-Chun Yang, Sheng-Ta Tsai, Berne Ting, Ying-Chih Cheng, Chin-Kun Wang, Jane Pei-Chen Chang, *Kuan-Pin Su. Psychological Outcomes and Quality of Life of Fibromyalgia Patients with Vitamin D Supplementation—A Meta-Analysis. J. Clin. Med. 2023, 12(7), 2750. IF= 2.9. (R/C= 65/332, Medicine, General & Internal)
2. Sheng-Ta Tsai, Srinivasan Nithiyanantham, Senthil Kumaran Satyanarayanan, *Kuan-Pin Su. Anti-Inflammatory Effect of Traditional Chinese Medicine on the Concept of Mind-Body Interface. Adv. Exp. Med. Biol. 2023;1411:435-458. IF= 3.650. (R/C= 33/94, Biology)
3. Sheng-Ta Tsai, Ming-Kuei Lu, Shao San, *Chon-Haw Tsai. The Neurologic Manifestations of Coronavirus Disease 2019 Pandemic: A Systemic Review. Front. Neurol. 2020 May 19;11:498. IF= 2.8. (R/C= 121/286, Clinical Neurology)
Original articles: (11)
|
1. Sheng-Ta Tsai, Mohamed M. El-Gohary, Maximiliano A. Hawkes, Amra Sakusic, Sangmun Hwang, Youngjong Kwak, Juan M. Rojas-Cabrera, Sara A. Vettleson-Trutza, Kristen M. Scheitler, Charles D. Blaha, John S. Kuo, Jin Woo Chang, Dong Pyo Jang, *Yoonbae Oh, *Kendall H. Lee, *Hojin Shin. Measuring vancomycin using paired pulse voltammetry with a wireless instantaneous neurotransmitter concentration sensing system for point-of-care patient treatment. Biomed. Eng. Lett. (2026). https://doi.org/10.1007/s13534-026-00580-1. IF= 2.8. (R/C= 66/124, Engineering, Biomedical) 2. Sheng-Ta Tsai, Zi-Lun Lai, Ming-Kuei Lu, Marina Walther-Antonio, Yi-Yao Hsu, Dy-San
Chao, Chia-Yang Chen, Sara Vettleson-Trutza, John S Kuo, Chia-Chun Yang,
Ching-Chu Chen, Po-Ren Hsueh, Der-Yang Cho, *Chon-Haw Tsai. Elevated Lactobacillus
salivarius and genus Akkermansia in fecal samples of Taiwanese
patients with Parkinson’s disease and diabetes mellitus. Sci. Rep.
15, 42261 (2025). IF= 3.9. (R/C= 25/136, Multidisciplinary science) 3. Hojin Shin, Kristen M. Scheitler, Juan
M. Rojas Cabrera, Abhinav Goyal, Joshua B. Boesche, Aaron E. Rusheen, Jason
Yuen, Barbara Hanna, Una Karanovic, Sara Vettleson-Trutza, Jennifer
Tang-Cabrera, Sheng-Ta Tsai, Mohamed Elgohary, Sara Hussein, Shiyuan
Wei, Lei Yuan, Malcolm McIntosh, Allen Rech, Marie Reyes, Warren O. Dennis,
Tyler J. Van Buren, Diane R. Eaker, Graham Cameron, Matt E. Hainy, Beverly J.
Berghuis, Christopher J. Kimble, Kevin E. Bennet, Basel Sharaf, Tyler S.
Oesterle, Xiaoke Chen, Zhenan Bao, Jaeyun Sung, Dong Pyo Jang, Charles D.
Blaha, Yoonbae Oh, *Kendall H. Lee. A multimodal platform for real-time
neurochemical and electrophysiologic monitoring for intraoperative
neurosurgical applications. Biosens. Bioelectron. Volume 293, 2026, 118151.
IF= 10.5. (R/C= 3/79, Biophysics)
4. Wei-Chun Wang, Shang-Yu Chien, Sheng-Ta
Tsai, Yu-Wan Yang, Dang-Khoa Nguyen, Ya-Lun Wu, Ming-Kuei Lu, Ting-Hsuan
Sun, Jiaxin Yu, Ching-Ting Lin, Chien-Wei Chen, Kai-Cheng Hsu, Chon-Haw Tsai.
Automated delineation of acute ischemic stroke lesions on non-contrast CT
using 3D deep learning: A promising step towards efficient diagnosis and
treatment. Biomed. Signal Process. Control 2024; 93:106139. IF= 4.9. (R/C= 32/124,
Engineering, Biomedical) 5.
Kuei-Ming Lin, Chen-En Wang, Hong-Ji
Liao, Wei-Laing Chen, Sheng-Ta Tsai, Shih-Hao Wu, Jia-Lun Huang,
*Chia-Wei Lin. A comparison of in-hospital stroke and community-onset stroke
outcomes after endovascular thrombectomy at a tertiary level hospital in
Taiwan. Neurol. Asia 2024; 29(1): 19- 25. IF= 0.3. (R/C= 280/286,
Clinical neurology) 6.
Sheng-Ta Tsai, Chia-Chun Yang, Hsien-Yin Liao, and *Yi-Wen Lin. Electroacupuncture
Reduces Fibromyalgia Pain via Neuronal/Microglial Inactivation and Toll-like
Receptor 4 in the Mouse Brain: Precise Interpretation of Chemogenetics.
Biomedicines 2024; 12(2): 387. IF= 3.9. (R/C= 114/320, Biochemistry and
molecular biology) 7.
Yu-Chen Chiu, Jia-Li Yang, Wei-Chun
Wang, Hung-Yu Huang, Wei-Liang Chen, Pao-Sheng Yen, Ying-Lin Tseng,
Hsiu-Hsueh Chen, *Sheng-Ta Tsai. Predictors of unfavorable outcome at
90 days in basilar artery occlusion patients. World J. Clin. Cases 2022;
10(12): 3677-3685. IF= 1.0. (R/C= 170/329, Medicine, General and Internal) 8.
Sheng-Ta Tsai, Tzu-Hsuan Wei, Yu-Wan Yang, Ming-Kuei Lu, Shao San, Chon-Haw Tsai,
*Yi-Wen Lin. Transient receptor potential V1 modulates neuroinflammation in
Parkinson’s disease dementia: Molecular implications for electroacupuncture
and rivastigmine. Iran. J. Basic Med. Sci. 2021; 24: 1-10. IF= 2.7. (R/C= 98/195,
Medicine, Research & Experimental) 9.
Sheng-Ta Tsai, *Fu-Yu Lin, Pei-Shan Chen, Hsiu-Yin Chiang, Chin-Chi Kuo. Three-year
mortality in cryptococcal meningitis: Hyperglycemia predict unfavorable
outcome. PLoS One. 2021 May 28;16(5):e0251749. IF= 2.6. (R/C= 44/136,
Multidisciplinary Sciences) 10. Sheng-Ta Tsai, Wei-Chun Wang, Yu-Ting Lin, Wei-Shih Huang, Hung-Yu Huang, Chun-Ju
Wang, En-Zu Lin, Wei-Ling Kung, Yuh-Cherng Guo, Kang-Hsu Lin, Ming-Kuei Lu,
Pao-Sheng Yen, Wei-Laing Chen, Ying-Lin Tseng, Chin-Chi Kuo, Der-Yang Cho,
Chun-Chung Chen, *Chon-Haw Tsai. Use of a smartphone application to speed up
interhospital transfer of acute ischemic stroke patients for thrombectomy.
Front. Neurol. 2021; 12: 606673. IF= 2.8. (R/C= 121/286, Clinical Neurology) 11.
Sheng-Ta Tsai, Chun-Hung Tseng, Mei-Chen Lin, Hsien-Yin Liao, Boon-Khai Teoh, Shao
San, Chon-Haw Tsai, Hung-Yu Huang, *Yi-Wen Lin. Acupuncture reduced the
medical expenditure in migraine patients: Real-world data of a 10-year
national cohort study. Medicine (Baltimore). 2020 Aug 7;99(32):e21345. IF= 1.4.
(R/C= 144/332, Medicine, General and Internal) Letter to the editor published as formal journal paper: (1) 1.
Kristen M Scheitler, Juan M
Rojas-Cabrera, Sara A Vettleson-Trutza, Sheng-Ta Tsai, Guillermo K
Pons-Monnier, Mohamed M El-Gohary, Ron Scheer, Youngjong Kwak, Damiano G
Barone, Charles D Blaha, Tyler S Oesterle, Hojin Shin, Kendall H Lee, Yoonbae
Oh. Application of a Human Stereotactic System for Image-Guided Deep Brain
Stimulation Neurosurgery in a Swine Model. Brain Stimul. 2025 Jul
11:S1935-861X(25)00275-X. IF= 8.4. (R/C= 13/286, Clinical Neurology) |
|
Case report published as formal journal paper: (7) |
|
1.
Shin-Kuang Jiang, Wei-Liang Chen, Chun Chien, Chi-Syuan
Pan, *Sheng-Ta Tsai. Rapid progressive vaccine-induced immune
thrombotic thrombocytopenia with cerebral venous thrombosis after ChAdOx1
nCoV-19 (AZD1222) vaccination: A case report. World. J. Clin. Cases 2022 Sep
16; 10(26): 9462-9469. IF= 1.0. (R/C= 170/329, Medicine,
General and Internal) 2.
Camerdy Yue Yang, *Sheng-Ta Tsai.
Glutamic acid decarboxylase 65-positive autoimmune encephalitis presenting
with gelastic seizure, responsive to steroid: A case report. World J. Clin.
Cases 2021; 9(19): 5325-5331. IF= 1.0. (R/C= 170/329, Medicine, General and
Internal) 3.
Ta-Wei Guu, Sheng-Ta Tsai, and *Kuan-Pin Su.
Autoimmune psychosis in Taiwan: A case report and review of literature. Brain.
Behav. Immun.-Health. 2020 Feb 25;3:100055. IF= 3.5. (R/C= 81/183,
Immunology) 4.
*Sheng-Ta Tsai, Wei-Shih Huang, Shin-Kuang Jiang, Hsien-Yin Liao. Cervical spinal
epidural abscess following needle-knife acupotomy, with an initial
presentation that mimicked an acute stroke: A case report. Hong Kong J. Emerg.
Med. 2020;27(2):99-102. IF= 0.8 (R/C= 39/56, Emergency Medicine) 5.
Sheng-Ta Tsai, Jheng-Zong Tien, Yin-Lan Lin, Yen-Cheng Lai, *An-Ti Chang.
Gastrointestinal: Refractory paralytic ileus cured by immunotherapy, a case
of natural killer cell neoplasm-induced polyneuropathy. J. Gastroenterol.
Hepatol. 2020 Dec 10. IF= 3.4. (R/C= 47/148, gastroenterology and hepatology) 6.
Shao Hor, Chih-Yu Chen, *Sheng-Ta
Tsai. Propofol pump controls nonconvulsive status epilepticus in a
hepatic encephalopathy patient: A case report. World J. Clin. Cases. 2019 Sep
26;7(18):2831-2837. IF= 1.0. (R/C= 170/329, Medicine, General and Internal) 7.
Shao San, Chia-der Lin, Sheng-Ta
Tsai, Chao-Chun Lin, *Po-Chang Wu. Immunoglobulin G4-Related Disease
Presented as Recurrent Otitis Media and Mixed Hearing Loss Treated with
Cyclophosphamide and Rituximab: A Case Report. Arch. Rheumatol. 2018 Nov
30;34(2):233-237. IF= 1.1 (R/C= 49/58, Rheumatology) |
2020年6月16日 星期二
個人簡歷
現職: 中國醫藥大學附設醫院主治醫師 (2019.08-)
經歷:
中華民國海軍陸戰隊醫務士 (2012.08-2013.07)
台中榮總不分科住院醫師 (2013.08-2014.07)
中國附醫神經部住院醫師 (2014.08-2019.07)
中國附醫神經部主治醫師 (2019.08-)
學歷: 國立成功大學醫學系學士 (2005.09-2012.06)
專科證照: 神經專科醫師
中華民國神經放射線醫學會動脈取栓認證
蒙古國義診
新冠肺炎疫情肆虐,海外義診皆暫停,翻到四年前到蒙古國義診時寫下的故事:
一、7/25(一) 烏理雅蘇臺 (Uliastai),一個13歲的小妹妹面色愁苦的過來,表示身上皮膚的斑點存在好幾個月了,時常很癢。小妹妹是牧區的孩子,每天要放牧牛羊、幫忙家人親戚洗衣服……,做許多的事情,很擔心這些斑點是不是什麼怪病,也受到親戚朋友的異樣眼光。
看完之後跟小妹妹解釋這是一種黴菌感染(變色糠疹,Tinea versicolor),不是怪病,只要抹藥膏、吃些藥就會好了!講完後聽著翻譯向小妹妹解釋,看著小妹妹的表情從愁苦變為開懷,最後很燦爛的向我們笑並答謝。
覺得很開心,但也看到當地醫療的貧乏,對疾病有許多似是而非的概念,且難以得到正確的諮詢,希望我們一些些的醫療知識,能夠幫忙解除他們身體及內心的痛苦。
二、一樣是 7/25(一) 烏理雅蘇臺 (Uliastai),一個59歲的阿伯,帕金森氏症,動作遲緩、左手顫抖、走路駝背,幫他做一些神經學檢查後開藥讓他帶回去,看完後阿伯伸出手來與我握手,「謝謝你專業的檢查!」
一時哽咽,在臺灣的帕金森氏症病人,追求的是更好的生活品質(手不抖、動作不要太慢…),但在這邊,接受幾分鐘的神經學檢查就很高興、知足、感恩,看到蒙古醫療的缺乏,和人民的純樸。
三、 7/31(日) 車金烏拉,昨天下午看的一個阿嬤跑來找我,想說「昨天不是看過了嗎?怎麼今天又來?」阿嬤透過翻譯跟我說「昨天腳痛來給你們看,看完回家後晚上第一次腳不會痛了,睡得很好,非常高興,想要來答謝你們。」
阿嬤向我們問了昨天壓的穴位點,向我們再三謝謝後離開,覺得很溫馨,雖然要坐車好幾個小時到蒙古的鄉村,但想到阿嬤的表情,覺得各種辛苦都是值得的。
四、 8/1(一) 陶宋冊格勒,最後一天的看診,下午有個 20 歲的年輕男孩過來,媽媽說他出生時跟正常人一樣,但是三歲的時候撞到頭,之後就開始會有癲癇發作,且智力比一般人差,看過後開些藥讓他回去。
當天我們約 19:30 結束看診,走出寺院時發現所有病人都回去了,剩下三個人留在外面:男孩、媽媽、和他的姊姊,男孩看到我走出門,便迎了上來,說了許多話,雖然聽不懂,但感受到他表情中的熱切,後來有個翻譯經過,便請他幫忙翻譯,他說男孩不停的講著一句話:
「我想要跟正常人一樣!」、「我想要跟正常人一樣!」、「我想要跟正常人一樣!」
多麼熱切的請求和渴望!但我此時此地卻幫不了他,只能建議他到大醫院就診,看能否用藥物將癲癇控制住。感受到一種自己能力不足的無力感,但是他的呼喚讓我想起之前看過的許多病人,「不分時空,大家希望解除病苦的心願是一樣的」,當時許下心願要好好學習,毋忘此刻,未來能幫助到他及許多有緣的人們,解除身體及心靈上的痛苦!
8/4(四)回到台灣,看到習慣的建築物、街道,很熟悉,也對乾淨的自來水、充足的電力、平整的路面、普及的沖水馬桶感到感恩,但內心時常會現起蒙古國廣闊的草原、藍天白雲、成群的牛羊馬、還有純樸但醫療資源缺乏的蒙古人們~












